Histologically Pure Stage I Seminoma With an Elevated β-hCG of 4497 IU/l - 09/08/11
Address for correspondence: Emil Totonchi, M.D., Department of Urology, Center for Urologic Health, Advocate Illinois Masonic Medical Center, 836 W Wellington Ave., Chicago, IL 60657.Résumé |
Approximately 30% of patients with pure seminoma of the testis have mild elevation of human chorionic gonadotropin (hCG) due to the presence of syncytiotrophoblastic giant cells. Levels are usually less than 500 IU/L; however, the occurrence of higher levels is rare. We report a case of a man with a stage I histologically pure seminoma, copious syncytiotrophoblast cells, and a serum beta human chorionic gonadotropin (β-hCG) of 4497 IU/L. To our knowledge this is the third highest value of β-hCG reported with a stage I pure seminoma. The patient underwent an orchiectomy and chemotherapy. His β-hCG level was undetectable by postoperative day 13, and he remains disease free at 30 months.
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Vol 70 - N° 5
P. 1007.e13-1007.e15 - novembre 2007 Retour au numéro
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