New Insight into Rectal Function in Pediatric Defecation Disorders: Disturbed Rectal Compliance is an Essential Mechanism in Pediatric Constipation - 10/08/11
, Rijk van Ginkel, MD, PhD, Marc A. Benninga, MD, PhD, Guus A. Hart, PhD, Jan A.J.M. Taminiau, MD, PhD, Guy E. Boeckxstaens, MD, PhD
Reprint requests: Wieger P. Voskuijl, MD, PhD, Department of Pediatric Gastroenterology and Nutrition, Room C2-312, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.Abstract |
Objective |
To evaluate rectal sensitivity in patients with pediatric constipation (PC) and nonretentive fecal soiling (FNRFS) using pressure-controlled distention (barostat).
Study design |
Thresholds for rectal sensitivity (first sensation, urge to defecate, and pain), and rectal compliance were determined using a barostat.
Results |
A total of 69 patients with PC (50 males; mean age, 10.9 ± 2.2 years) and 19 patients with FNRFS (15 males; mean age, 10.0 ± 1.9 years) were compared with 22 healthy volunteers (HVs) (11 males; mean age, 12.7 ± 2.6 years). Sensitivity thresholds were not significantly different among the 3 groups. Rectal compliance was increased in 58% of the patients with PC (P < .0001 vs HVs). Rectal compliance did not differ between patients with FNRFS and HVs. Children with PC with abnormal rectal function required significantly larger rectal volumes at urge to defecate.
Conclusions |
Increased compliance is the most prominent feature in patients with PC. Because of higher compliance in these children, larger stool volumes are required to reach the intrarectal pressure of the urge to defecate. Children with FNRFS have normal rectal function.
Le texte complet de cet article est disponible en PDF.Mots-clés : FNRFS, HV, MDP, NS, PC, SD
Plan
Vol 148 - N° 1
P. 62-67 - janvier 2006 Retour au numéro
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