Spinal-Cord MRI in Multiple Sclerosis: Conventional and Nonconventional MR Techniques - 11/08/11
, Frederik Barkhof, MD, PhD
Corresponding author.Abstract |
Multiple sclerosis is a diffuse disease of the central nervous system, and MRI of the spinal cord is highly recommended in the clinical evaluation of patients suspected of having multiple sclerosis. Within the new diagnostic criteria, spinal cord MRI increases sensitivity and possibly specificity for MS, but further work is needed to investigate other criteria that may give greater weight to the presence of cord lesions in patients with clinically isolated syndromes or suspected relapsing-remitting multiple sclerosis. Techniques should be further studied and validated in studies comparing these techniques with clinical status and histopathology, however.
Le texte complet de cet article est disponible en PDF.Keywords : Multiple sclerosis, Magnetic resonance imaging, Spinal cord, Atrophy, DWI, Spectroscopy, Functional MRI, Demyelination
Plan
| Search strategy and selection criteria: Data for this review were identified by searches of MEDLINE with the terms “multiple sclerosis”, “magnetic resonance imaging”, “spinal cord”, “atrophy”, “DWI”, “spectroscopy”, “functional MRI” and “demyelination”. Further, articles identified through searches of the files of the authors, and through references cited in the articles were used. Only papers published in English were reviewed. Precise information on unpublished or in-press data was obtained through personal communication with researchers who work in the same research groups as the authors. In clinical work-up of clinically isolated syndrome patients imaging of the spinal cord has become a useful tool. |
Vol 19 - N° 1
P. 81-99 - février 2009 Retour au numéro
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