Coronary MR Imaging: Lumen and Wall - 11/08/11

Doi : 10.1016/j.mric.2008.12.003

Sebastian Kelle, MD ^a,^b, Robert G. Weiss, MD ^b,^c, Matthias Stuber, PhD ^b,^c,^d,^⁎
^a Division of Cardiology, Department of Medicine, German Heart Institute, Berlin, Germany
^b Division of Magnetic Resonance Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
^c Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
^d Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA

Corresponding author. Department of Radiology, Johns Hopkins University School of Medicine, Park Building, Room 338, 600 North Wolfe Street, Baltimore, MD 21287, USA.

Abstract

Coronary MR imaging is a promising noninvasive technique for the combined assessment of coronary artery anatomy and function. Anomalous coronary arteries and aneurysms can reliably be assessed in clinical practice using coronary MR imaging and the presence of significant left main or proximal multivessel coronary artery disease detected. Technical challenges that need to be addressed are further improvements in motion suppression and abbreviated scanning times aimed at improving spatial resolution and patient comfort. The development of new and specific contrast agents, high-field MR imaging with improved spatial resolution, and continued progress in MR imaging methods development will undoubtedly lead to further progress toward the noninvasive and comprehensive assessment of coronary atherosclerotic disease.

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Keywords : Coronary MR imaging, Vessel wall, Imaging, Atherosclerosis, Vessel lumen

Plan

Technical considerations for coronary MR imaging

Cardiac motion

Respiratory motion

Contrast enhancement in coronary MR imaging

Coronary artery lumen imaging for detection of significant stenoses

Imaging of coronary artery bypass grafts

Anomalous coronary arteries

Coronary artery aneurysms

Coronary artery flow measurement

Coronary endothelial function

Coronary vessel wall imaging

Coronary vessel wall delayed enhancement

Molecular targeted imaging

High-field coronary artery imaging

Summary

Dr. Kelle is supported by a scholarship from the German Cardiac Society. This work was supported by National Institutes of Health grant R01-HL084186; R01-HL61912 and by the Donald W. Reynolds Foundation. Dr. Stuber was compensated as a consultant by Philips Medical Systems, The Netherlands, the manufacturer of the equipment described in this article. The terms of this agreement have been approved by the Johns Hopkins University in accordance with its conflict of interest policies.