Newer Therapeutic Approaches: Gout - 12/08/11
Doi : 10.1016/j.rdc.2005.10.003
H. Ralph Schumacher, MD a, b, ⁎ 
, Lan X. Chen, MD, PhD a, b, c
, Lan X. Chen, MD, PhD a, b, c a Division of Rheumatology, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA
b University of Pennsylvania School of Medicine, Philadelphia, PA, USA
c Penn–Presbyterian Medical Center, Philadelphia, PA, USA
⁎Corresponding author. Division of Rheumatology, Philadelphia Veterans Affairs Medical Center–151K, University and Woodlands Avenues, Philadelphia, PA 19104
Résumé |
Newer approaches to the treatment of gout have included modifications and further attention to aspects of current therapies, and development of interesting new therapies. Colchicine prophylaxis appears to be needed longer than previously recognized after introduction of a urate-lowering agent. Diet has received attention, though most dietary effects are small. New agents under investigation include pegylated formulations of uricase and a new potent xanthine oxidase inhibitor, febuxostat. Some cardiovascular drugs have been shown to be uricosuric.
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| Dr. Schumacher and Dr. Chen have received research grants from TAP Pharmaceuticals. Dr. Schumacher has received research grants from Merck. |
© 2005
Publié par Elsevier Masson SAS.
Vol 32 - N° 1
P. 235-244 - février 2006 Retour au numéro
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