Melanoma Epidemiology - 12/08/11
Doi : 10.1016/j.hoc.2009.03.010
Margaret A. Tucker, MD a, b, ⁎ 
a Human Genetics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7122, Bethesda, MD 20892-7236, USA
b Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7122, Bethesda, MD 20892-7236, USA
Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7122, Bethesda, MD 20892-7236, USA.Abstract |
Melanoma is a complex, heterogeneous cancer that continues to increase in incidence. Multiple studies have consistently identified major host and environmental risk factors for melanoma. Nevi, particularly dysplastic nevi, confer much higher risks than most pigmentary characteristics. Ultraviolet radiation exposure is the predominant environmental risk factor for melanoma. Recently, both rare high risk susceptibility genes and common polymorphic genes contributing to melanoma risk have been identified.
Le texte complet de cet article est disponible en PDF.Keywords : Melanoma, Risk factors, Nevi, UV, Genetics
Plan
| This work was supported by the Intramural Research Program, NCI, NIH. |
© 2009
Publié par Elsevier Masson SAS.
Vol 23 - N° 3
P. 383-395 - juin 2009 Retour au numéro
Article précédent
- Preface
- David E. Fisher
- Applications of Genomics in Melanoma Oncogene Discovery
- Michael F. Berger, Levi A. Garraway
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?