A randomized, double-blinded, controlled trial comparing parenteral normal saline with and without dextrose on the course of labor in nulliparas - 13/08/11
Résumé |
Objective |
The objective of the study was to compare intravenous normal saline with and without dextrose on the course of labor in nulliparae.
Study Design |
In a double-blinded, controlled trial, term, nulliparae with singletons in active labor were randomized into 1 of 3 groups receiving either normal saline (NS), NS with 5% dextrose (D5NS), or NS with 10% dextrose (D10NS) at 125 mL/h. The primary outcome was total length of labor from onset of study fluid in vaginally delivered subjects. Maternal and neonatal outcomes were also analyzed.
Results |
Of 300 subjects enrolled, 289 met inclusion criteria and completed the study. In vaginally delivered subjects, significant differences were noted in the second stage (P = .01) and total length of labor (P = .02). No significant differences were observed in the cesarean section rates between the groups (P = .21). No differences were noted in maternal or neonatal secondary outcomes.
Conclusion |
Administration of a dextrose solution, regardless of concentration, was associated with a shortened labor course in term vaginally delivered nulliparae subjects in active labor.
Le texte complet de cet article est disponible en PDF.Key words : dextrose, dystocia, hydration, labor, nulliparae
Plan
| Cite this article as: Shrivastava VK, Garite TJ, Jenkins SM, et al. A randomized, double-blinded, controlled trial comparing parenteral normal saline with and without dextrose on the course of labor in nulliparas. Am J Obstet Gynecol 2009;200:379.e1-379.e6. |
|
| Reprints not available from the authors. |
|
| This study was supported in part by the MemorialCare Foundation. |
Vol 200 - N° 4
P. 379.e1-379.e6 - avril 2009 Retour au numéro
Article précédent
- First-trimester cervical inflammatory milieu and subsequent early preterm birth
- Hyagriv N. Simhan, Marijane A. Krohn
- The diagnostic dilemma of thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in the obstetric triage and emergency department: lessons from 4 tertiary hospitals
- Caroline L. Stella, John Dacus, Edwin Guzman, Pushpinder Dhillon, Kristin Coppage, Helen How, Baha Sibai
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?