Tumor Microenvironment and the Immune Response - 15/08/11
Doi : 10.1016/j.soc.2007.07.002
Silvia Selleri, PhD a, b, Cristiano Rumio, PhD b, Marianna Sabatino, MD a, Francesco M. Marincola, MD a, Ena Wang, MD a, ⁎ 
a Infectious Disease and Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
b Universita’ degli Studi di Milano, Department of Human Morphology, via Mangiagalli 31, 20133 Milan, Italy
Corresponding author.Abstract |
Without clinical information, accurate follow-up, high-quality sample collection, and preservation, scientific conclusions are only based on theoretical assumptions that are unlikely to lead to clinical breakthroughs. In this article we discuss our understanding of the relationship between cancer cells and the host immune response. We emphasize the critical role that future clinical investigations, led by surgical oncologists, may have for the assessment of the validity of the disparate hypotheses so far formulated at the bench side.
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| Silvia Selleri is partially supported by FIRC (Federazione Italiana per la Ricerca sul Cancro). |
© 2007
Publié par Elsevier Masson SAS.
Vol 16 - N° 4
P. 737-753 - octobre 2007 Retour au numéro
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