3. Cytokines and chemokines - 15/08/11
, Larry Borish, MD
Reprint requests: John W. Steinke, PhD, Asthma and Allergic Disease Center, Beirne Carter Center for Immunology Research, University of Virginia Health Systems, PO Box 801355, Charlottesville, VA 22908-1355.Charlottesville, VaThis activity is available for CME credit. See page 5A for important information.
Abstract |
Cytokines and chemokines are secreted proteins with growth, differentiation, and activation functions that regulate the nature of immune responses. Cytokines are involved in nearly every facet of immunity and inflammation, from induction of the innate immune response to the generation of cytotoxic T cells and the development of antibodies by the humoral immune system. The combination of cytokines that are produced in response to an immune insult determines which arm of the immune system will be activated. For this update, recent advances in our understanding of cytokines will be discussed, which includes the IL-10, IL-17, and IL-27 families.
Le texte complet de cet article est disponible en PDF.Key words : Interleukin, cytokine, chemokine, T cell
Abbreviations used : APC, NK, Treg cell
Plan
Vol 117 - N° 2S2
P. S441-S445 - février 2006 Retour au numéro
Article précédent
- 2. Update on primary immunodeficiency diseases
- Francisco A. Bonilla, Raif S. Geha
- 4. Autoimmunity, vasculitis, and autoantibodies
- Susan J. Lee, Arthur Kavanaugh
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