Limbal Stem Cell Deficiency After Subconjunctival Mitomycin C Injection for Trabeculectomy - 18/08/11
Inquiries to Jost B. Jonas, MD, Universitäts-Augenklinik, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, GermanyRésumé |
Purpose |
To report on severe limbus cell insufficiency after trabeculectomy with subconjunctival injection of mitomycin C.
Design |
Interventional small case-series.
Methods |
Seven consecutive Caucasian patients (seven eyes) underwent penetrating trabeculectomy that included subconjunctival injection of 0.1 to 0.2 ml of mitomycin C (0.2 mg/ml) at the 12 o’clock position.
Results |
All patients with a follow-up time of >1.5 years (n = 3 eyes; 43%) experienced marked ocular surface problems that included corneal thinning (n = 1) and scleral melting (n = 2). Four patients (57%) with a follow-up time of <14 months did not show complications that were attributable to the subconjunctival application of mitomycin.
Conclusions |
Because limbal stem cell deficiency may be a late complication of subconjunctival mitomycin C injection, subconjunctival injection of mitomycin C may be avoided in routine antiglaucomatous filtering surgery.
Le texte complet de cet article est disponible en PDF.
Vol 141 - N° 6
P. 1129-1130 - juin 2006 Retour au numéro
Article précédent
- Zone 1 Retinopathy of Prematurity in a Transitional Economy: A Cautionary Note
- Susan M. Carden, Luu Ngoc Lan, Tess Huynh
- Sustained Effect of Travoprost on Diurnal and Nocturnal Intraocular Pressure
- Arthur J. Sit, Robert N. Weinreb, Jonathan G. Crowston, Daniel F. Kripke, John H.K. Liu
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?