Survival and major neonatal complications in infants born between 22 0/7 and 24 6/7 weeks of gestation (1999-2003) - 18/08/11
, Andreas Schulze, MD a, Angela Kribs, MD b, Bernhard Roth, MD b, Wolfgang Lindner, MD c, Frank Pohlandt, MD, MS c
Reprint requests: Susanne Herber-Jonat, MD, Department of Obstetrics and Gynecology, Division of Neonatology, Ludwig Maximilian University of Munich, Klinikum Grosshadern, Marchioninistr. 15, D-81377 Munich.Abstract |
Objective |
This study was undertaken to compare survival and morbidity until discharge in infants born after 22-23 versus 24 weeks’ gestational age (GA).
Study design |
Cohort study of all infants 25 weeks or less, born in 3 tertiary perinatal centers (1999-2003).
Results |
Of a total of 336 infants, 133 (40%) died before or immediately after birth without the provision of life support, 203 (60%) received active neonatal treatment. Infants with life support (n = 82 at 22 to 23 weeks, n = 121 at 24 weeks) differed with respect to antenatal steroid prophylaxis (44% vs 62%) and cesarean section rate (51% vs 71%). Survival was 67% compared with 82% (P = .016). The incidence of intraventricular hemorrhage III or greater or periventricular leukomalacia (15/15%), severe retinopathy of prematurity (18/15%), and chronic lung disease (40/47%) was similar in both GA groups.
Conclusions |
The provision of life support for extremely preterm infants increases their chance of survival without more neonatal morbidity.
Le texte complet de cet article est disponible en PDF.Key words : Infant, Premature, Morbidity, Survival, Outcome, Border of viability, Very low birth weight
Plan
Vol 195 - N° 1
P. 16-22 - juillet 2006 Retour au numéro
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