Pathophysiology of Pneumonia - 18/08/11
Doi : 10.1016/j.ccm.2004.10.013
Amalia Alcón, MD, PhD a, Neus Fàbregas, MD, PhD a, Antoni Torres, MD, PhD b, ⁎ 
a Surgical Intensive Care Unit, Anesthesiology Department, Hospital Clínic, Villarroel 170, Barcelona 08036, Spain
b Institut Clínic de Pneumología I Cirurgía Torácica, IDIBAPS Universitat de Barcelona, Villarroel 170, Barcelona 08036, Spain
*Corresponding author. Servicio de Pneumología, Hospital Clínic, Villarroel 170, Barcelona 08036, Spain
Résumé |
The development of pneumonia requires that a pathogen reach the alveoli and that the host defenses are overwhelmed by microorganism virulence or by the inoculum size. The endogenous sources of microorganisms are nasal carriers, sinusitis, oropharynx, gastric, or tracheal colonization, and hematogenous spread. Other external sources of contamination, such as intensive care unit workers, aerosols, or fibrobronchoscopy, must be considered as accidental.
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| This article was supported by Red Gira 03/063, Red Respira 03/11, Instituto Carlos III and FIS non-responding PI020616. |
© 2005
Elsevier Inc. Tous droits réservés.
Vol 26 - N° 1
P. 39-46 - mars 2005 Retour au numéro
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