Conjunctival lymphoid hyperplasia presenting with bilateral panuveitis - 18/08/11
Inquiries to Alexander S. Ioannidis, Royal Free Hospital, Pond Street, London NW3 2 QGRésumé |
Purpose |
To report on a case of bilateral conjunctival lymphoid hyperplasia presenting with bilateral panuveitis in a female patient.
Design |
Observational case report.
Methods |
In this case excisional biopsy indicated lymphoid tissue. Immunohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes.
Results |
Causes of panuveitis were considered and excluded based on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal.
Conclusions |
Ocular adnexal lymphoproliferative lesions consist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical criteria to differentiate between these lesions. This case highlights the importance of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we advocate periodic follow-up examinations because of the small potential risk of developing ocular or systemic lymphoma in these patients.
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Vol 139 - N° 3
P. 566-568 - mars 2005 Retour au numéro
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