Corneal Pseudomembrane From Acute Inflammatory Response and Fibrin Formation to Acute Myeloid Leukemic Infiltrate - 18/08/11
, Hanna Coleman, MD, Chi-Chao Chan, MDRésumé |
Purpose |
To describe an unusual ocular manifestation of a patient with acute myeloid leukemia (AML).
Design |
Observational case report.
Methods |
A 59-year-old woman with a history of preleukemic myelodysplastic syndrome (MDS) and status post bone marrow transplant (BMT) complained of a sudden onset of poor vision associated with a corneal pseudomembrane. Ocular graft vs host disease was suspected, and the pseudomembrane was excised for histopathologic examination.
Results |
The pseudomembrane showed myeloblasts admixed with an acute inflammatory response suggestive of the development of AML, a complication of MDS. Bone marrow examination confirmed the diagnosis of relapsing AML.
Conclusions |
Acute myeloid leukemia could present as a pseudomembrane; thus, examination of relevant ocular tissue is recommended.
Le texte complet de cet article est disponible en PDF.Vol 139 - N° 5
P. 921-923 - mai 2005 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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