Visual Side Effects Associated with Erectile Dysfunction Agents - 18/08/11
Inquiries to Frederick W. Fraunfelder, MD, Casey Eye Institute, 3375 S.W. Terwilliger Blvd., Portland, OR 97239-4197; fax: (503) 418-2284Résumé |
Purpose |
To describe the known ocular side effects of agents used to treat erectile dysfunction.
Design |
Retrospective observational case series and literature review.
Methods |
We reviewed 892 case reports from the National Registry of Drug-Induced Ocular Side Effects (Casey Eye Institute, Portland, Oregon), the Food and Drug Administration (FDA), and the World Health Organization (WHO) and conducted a comprehensive review of the literature.
Results |
Ocular side effects of these drugs appear fully reversible and transitory.
Conclusions |
To date, evidence does not exist to discourage use of erectile dysfunction agents attributable to harmful ocular side effects. Ischemic optic neuropathy (ION) is “possible” by WHO classification, however, conclusive evidence linking ION to erectile dysfunction medications is still lacking.
Le texte complet de cet article est disponible en PDF.| See accompanying editorial in this issue. This study was supported in part by an unrestricted grant from Research to Prevent Blindness, New York, New York, and by the National Registry of Drug-Induced Ocular Side Effects, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon. The author is indebted to The National Registry of Drug-Induced Ocular Side Effects, the Food and Drug Administration, and the World Health Organization in this study that contributed data. However, the opinions and conclusions expressed are not necessarily those of the various centers or of the WHO. The author has no proprietary interest in these materials. |
Vol 140 - N° 4
P. 723-724 - octobre 2005 Retour au numéro
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