Microarray technology in obstetrics and gynecology: A guide for clinicians - 18/08/11
Reprint requests: Kenneth Ward, MD, Professor and Chair, University of Hawaii, Department of Obstetrics, Gynecology, and Women’s Health, Kapiolani Hospital, 1319 Punahou Street, Room 824, Honolulu, HI 96826.Abstract |
Microarrays can be constructed with dozens to millions of probes on their surface to allow high-throughput analyses of many biologic processes to be performed simultaneously on the same sample. Microarrays are now widely used for gene expression analysis, deoxyribonucleic acid resequencing, single-nucleotide polymorphism genotyping, and comparative genomic hybridization. Microarray technology is accelerating research in many fields and now microarrays are moving into clinical application. This review discusses the emerging role of microarrays in molecular diagnostics, pathogen detection, oncology, and pharmacogenomics.
Le texte complet de cet article est disponible en PDF.Key words : Microarray, Genomics, Gene mapping, Gene expression
Plan
| Supported by grants from the National Institutes of Health (5 K24 HD01315-02 and 2 U 54 RR014607-06 from the Research Centers in Minority Institutions program in the National Center for Research Resources). |
Vol 195 - N° 2
P. 364-372 - août 2006 Retour au numéro
Article précédent
- High-dimensional biology in obstetrics and gynecology: Functional genomics in microarray studies
- Roberto Romero, Gerard Tromp
- Analysis of microarray experiments of gene expression profiling
- Adi L. Tarca, Roberto Romero, Sorin Draghici
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