Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia - 19/08/11
, Ambarina Faiz, MD, MPH a, John A. Heit, MD b, Peter A. Kouides, MD c, Andrea Lukes, MD d, Sidney F. Stein, MD e, Vanessa Byams, MPH f, Connie H. Miller, PhD f, Roshni Kulkarni, MD f, g
Reprints: Claire Philipp, MD, Division of Hematology, UMDNJ-Robert Wood Johnson Medical School, PO Box 19, MEB Rm 378, New Brunswick, NJ 08903Résumé |
Objective |
The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.
Study Design |
Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders.
Results |
Two hundred and seventeen women who were identified with a PBAC score of ≥100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively.
Conclusion |
This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.
Le texte complet de cet article est disponible en PDF.Key words : bleeding disorder, ferritin, hemostatic evaluation, menorrhagia
Plan
| Supported by the Association of Teachers of Preventive Medicine/Centers for Disease Control and Prevention (C.S.P., J.A.H., P.A.K., A.L., RK, and S.F.S.). |
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| The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention. |
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| Cite this article as: Philipp CS, Faiz A, Heit JA, et al. Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia. Am J Obstet Gynecol 2011;204:209.e1-7. |
Vol 204 - N° 3
P. 209.e1-209.e7 - mars 2011 Retour au numéro
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