Second Symposium on the Definition and Management of Anaphylaxis: Summary Report—Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium - 19/08/11

Doi : 10.1016/j.annemergmed.2006.01.018

Hugh A. Sampson, MD ^a, Anne Muñoz-Furlong, BA ^b, Ronna L. Campbell, MD, PhD ^c, N. Franklin Adkinson, MD ^d, S. Allan Bock, MD ^e, Amy Branum, MD ^f, Simon G.A. Brown, MD ^g, Carlos A. Camargo, MD ^h, Rita Cydulka, MD ⁱ, Stephen J. Galli, MD ^j, Jane Gidudu, MD ^k, Rebecca S. Gruchalla, MD ^l, Allen D. Harlor, MD ^m, David L. Hepner, MD ⁿ, Lawrence M. Lewis, MD ^o, Phillip L. Lieberman, MD ^p, Dean D. Metcalfe, MD ^q, Robert O’Connor, MD ^r, Antonella Muraro, MD ^s, Amanda Rudman, BA ^q, Cara Schmitt, MS ^b, Debra Scherrer, BA ^b, F. Estelle Simons, MD ^t, Stephen Thomas, MD ^u, Joseph P. Wood, MD ^v, Wyatt W. Decker, MD ^c,^⁎
^a Mount Sinai School of Medicine, New York, NY
^b Food Allergy and Anaphylaxis Network, Fairfax, VA
^c Mayo Clinic, Rochester, MN
^d Johns Hopkins University School of Medicine, Baltimore, MD
^e Food Allergy and Anaphylaxis Network, Boulder, CO
^f National Center for Health Statistics, Hyattsville, MD
^g Fremantle Hospital, Fremantle, WA, Australia
^h Massachusetts General Hospital, Boston, MA
ⁱ Case Western Reserve University School of Medicine, Cleveland, OH
^j Stanford University School of Medicine, Stanford, CA
^k Centers for Disease Control and Prevention, Lilbum, GA
^l University of Texas Southwestern Medical Center, Dallas, TX
^m American Academy of Pediatrics, Eugene, OR
ⁿ American Society of Anesthesiologists, Boston, MA
^o Society for Academic Emergency Medicine, St. Louis, MO
^p American College of Allergy, Asthma, and Immunology, Cordova, TN
^q National Institute of Allergy and Infectious Diseases, and the National Institutes of Health, Bethesda, MD
^r National Association of EMS Physicians, Baltimore, MD
^s University of Padua, Padua, Italy
^t American Academy of Allergy, Asthma, and Immunology, Winnipeg, Manitoba, Canada
^u American College of Emergency Physicians, Dallas, TX
^v American Academy of Emergency Medicine, Scottsdale, AZ.

Address for correspondence: Wyatt W. Decker, MD, Mayo Clinic, 200 First Street SW, Rochester, MN 55905; 507-255-6501, fax 507-255-6592

Résumé

There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.

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Plan

Definition of anaphylaxis and criteria for diagnosis

Management of anaphylaxis

Epinephrine

Oxygen and adrenergic agonists

Positioning of the patient

Fluid resuscitation

Vasopressors

H₁- and H₂-antihistamines

Corticosteroids

Glucagon for persistent hypotension in patients taking β-blockers

Observation

Outpatient follow-up and management

Research needs

Due to its nature as the collective recommendations of a group of experts and another specialty society, this article was peer reviewed only by Annals editorial board members.
This article originally published in the February 2006 issue of The Journal of Allergy and Clinical Immunology.
This article is being reprinted in Annals of Emergency Medicine with permission.

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Vol 47 - N° 4

P. 373-380 - avril 2006 Retour au numéro

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Second Symposium on the Definition and Management of Anaphylaxis: Summary Report—Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium - 19/08/11

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