Third-Generation Optical Coherence Tomography Findings in Punctate Retinal Toxoplasmosis - 19/08/11
, Wesley Campos, MD, PhD a, Daniela Calucci, COMT a, Ingrid U. Scott, MD, MPH c, Fernando Oréfice, MD, PhD a
Inquiries to Rogério A. Costa, MD, PhD, Unidade de Diagnostico Avancado e Tratamento – Hospital de Olhos de Araraquara, Rua Padre Duarte 989 apto 172, Araraquara-SP, 14801-310 BrazilRésumé |
Purpose |
To investigate optical coherence tomography (OCT) findings in patients with punctate retinal toxoplasmosis (PRT).
Design |
Observational case series.
Methods |
Setting: Tertiary ophthalmic referral center. Study Population: Four patients with PRT consecutively evaluated between July 2004 and June 2005. Observation Procedures: Clinical examination and OCT. Main Outcome Measures: Morphologic features at baseline and changes within a 24-week follow-up interval.
Results |
Retinal layers were abnormally hyperreflective at the active lesion site and associated with some degree of retinal pigment epithelium-choriocapillaris/choroidal optical shadowing in all patients. The posterior hyaloid was thickened and focally detached (over the lesion). Additional findings include tractional maculopathy (n = 2) and diffuse macular edema (n = 1). During follow-up, focal choriocapillaris/choroidal relative hyperreflectivity was observed at the former lesion site, and posterior vitreous detachment progressed in all patients.
Conclusions |
Our findings suggest that OCT may enable identification of subtle morphologic features previously underappreciated in patients with PRT, which may provide new insights about the disease pathophysiologic mechanisms.
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Vol 142 - N° 3
P. 503 - septembre 2006 Retour au numéro
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