Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women? - 19/08/11

Doi : 10.1016/j.ajog.2010.06.025

John Owen, MD, MSPH ^a, Jeff M. Szychowski, PhD ^b, Gary Hankins, MD ^c, Jay D. Iams, MD ^d, Jeanne S. Sheffield, MD ^e, Annette Perez-Delboy, MD ^f, Vincenzo Berghella, MD ^g, Deborah A. Wing, MD ^h, Edwin R. Guzman, MD ⁱ
Vaginal Ultrasound Trial Consortium
^a Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL
^b Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL
^c Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX
^d Department of Obstetrics and Gynecology, The Ohio State University Medical Center, Columbus, OH
^e Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX
^f Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY
^g Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA
^h Department of Obstetrics and Gynecology, University of California, Irvine, Irvine, CA
ⁱ Department of Obstetrics and Gynecology, Saint Peter's University Hospital, New Brunswick, NJ

Résumé

Objective

We sought to assess pregnancy outcome along a continuum of cervical lengths (CLs) ≥25 mm.

Study Design

We conducted planned secondary analysis of a randomized cerclage trial of women with prior spontaneous preterm birth 17⁰-34^6/7 weeks. Outcomes of women who maintained CLs ≥25 mm were analyzed. Women with CLs <25 mm randomized to no cerclage comprised an internal comparison group.

Results

Of 1014 screened, 153 had CL <25 mm, and 672 had CL ≥25 mm. Birth <35 weeks occurred in 16% of the ≥25 mm cohort. The relationship between CLs ≥25 mm and birth gestational age was null (P = .15). In the <25 mm group, progressively shorter CLs predicted birth <35 weeks (P < .001); this relationship was null in the ≥25 mm group (P = .17).

Conclusion

The continuum of CLs ≥25 mm measured between 16^0/7-22^6/7 weeks does not predict gestational length in women with prior spontaneous preterm birth.

Le texte complet de cet article est disponible en PDF.

Key words : cervical length, preterm birth prediction, prior preterm birth, vaginal sonography

Plan

Materials and Methods

Results

Comment

	The other members of the Vaginal Ultrasound Trial Consortium are listed with the full-length article at www.AJOG.org.
	The Eunice Kennedy Shriver National Institute of Child Health and Human Development provided funding via Grant no. U01 HD039939. From the same agency, Dr Owen received support via Grant no. 5K24 HD43314-5.
	Reprints not available from the authors.
	Cite this article as: Owen J, Szychowski JM, Hankins G, et al. Cervical lengths ≥25 mm and preterm birth. Am J Obstet Gynecol 2010;203:393.e1-5.

Export

Vol 203 - N° 4

P. 393.e1-393.e5 - octobre 2010 Retour au numéro

Article précédent

Complete trisomy 21 vs translocation Down syndrome: a comparison of modes of ascertainment
Eran Bornstein, Erez Lenchner, Alan Donnenfeld, Cristiano Jodicke, Sean M. Keeler, Sara Kapp, Michael Y. Divon

| Article suivant

Ultrasound prediction of birthweight and growth restriction in fetal gastroschisis
Padmashree Chaudhury, Sina Haeri, Amanda L. Horton, Honor M. Wolfe, William H. Goodnight

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.

Déjà abonné à cette revue ?

connectez-vous ou créez un compte

Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women? - 19/08/11

Résumé

Objective

Study Design

Results

Conclusion

Plan

Export citations

Fichier

Contenu

Accès rapides

Mon compte

Aide & support

Plateformes Elsevier Masson

Déclaration CNIL