Potential for Altering Rheumatoid Arthritis Outcome - 19/08/11
Doi : 10.1016/j.rdc.2005.07.008
Mark A. Quinn, MBChB, MRCP a, Paul Emery, MA, MD, FRCP a, b, ⁎ 
a Academic Unit of Musculoskeletal Disease, Department of Rheumatology, Chapel Allerton Hospital, Leeds, UK
b Leeds Teaching Hospitals Trust, Chapel Allerton Hospital, Leeds, UK
⁎Corresponding author. Academic Unit of Musculoskeletal Disease, Department of Rheumatology, Chapel Allerton Hospital, 2nd Floor, Chapel Town Road, Leeds LS7 4SA, UK
Résumé |
The potential for disproportionately altering outcome in the early stages of rheumatoid arthritis (RA) was first hypothesized in the early 1990s. This window of opportunity hypothesis for therapeutic intervention in RA is based on the existence of a time frame within which there is a potential for a greater response to therapy, resulting in sustained benefits or, perhaps most important, a chance of cure. Given the persistent, progressive, damaging, inflammatory nature of RA, this approach to altering outcome in the early stages seems attractive.
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© 2005
Elsevier Inc. Tous droits réservés.
Vol 31 - N° 4
P. 763-772 - novembre 2005 Retour au numéro
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