Comparison of Retinal Vessel Measurements in Digital vs Film Images - 19/08/11

Doi : 10.1016/j.ajo.2006.05.056

Anne Mosher, BS ^a,^⁎ , Barbara E.K. Klein, MD, MPH ^a, Ronald Klein, MD, MPH ^a, Michael D. Knudtson, MS ^a, Nicola J. Ferrier, PhD ^b
^a Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School Madison, Madison, Wisconsin
^b Department of Mechanical Engineering, University of Wisconsin, Madison, Wisconsin.

Inquiries to Anne Mosher, BS, University of Wisconsin Madison, Department of Ophthalmology and Visual Sciences, 610 N. Walnut Street, 4th Floor WARF, Madison, WI 53726

Résumé

Purpose

To compare central retinal artery equivalents (CRAE) and central retinal vein equivalents (CRVE) from vessels measured from images captured with a digital camera and digitized images taken with a film camera.

Design

Comparison of techniques.

Methods

Setting: Clinic. Patients: A total of 75 eyes of 48 adults. Observation procedures: Gradings of retinal vessel diameters from images produced by using two photographic techniques: directly from a 45° digital camera and digitized by scanning from a 30° film-based camera. Main outcome measure: Differences in CRAE and CRVE from two types of images.

Results

CRAE and CRVE were highly comparable between the two techniques with correlation coefficients of 0.88 and 0.87, respectively.

Conclusion

Estimates of CRAE and CRVE from measurements taken from digitally captured and digitized film-based images were highly comparable. It is likely that inferences about factors associated with retinal vessel diameters will be unbiased by the method of imaging.

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Supported by National Institutes of Health Grant No. EY06594 (R.K., B.E.K.K.) and, in part, by the Research to Prevent Blindness (R.K., B.E.K.K) Senior Scientific Investigator Awards, New York, New York.