Rectal colonization by group B Streptococcus as a predictor of vaginal colonization - 20/08/11
Résumé |
Objective |
The purpose of this article was to describe rectal colonization by group B Streptococcus (GBS) and its role in the prediction of vaginal colonization.
Study Design |
In this prospective cohort of 1248 nonpregnant women, vaginal and rectal swabs for GBS culture were obtained at enrollment and at three 4-month intervals. Generalized estimating equations were used to identify factors that are associated with colonization.
Results |
Eight hundred fourteen (65%) women had GBS colonization sometime during the observation period. Rectal GBS colonization was the strongest predictor of vaginal colonization (adjusted odds ratio, 14.3; 95% CI, 11.9-17.1). Recent sexual intercourse, vaginal colonization with yeast, and a vaginal Nugent score ≥ 4 were also independent determinants of vaginal GBS colonization. Antimicrobial use decreased vaginal GBS colonization only among women who had no rectal colonization.
Conclusion |
GBS in the gastrointestinal tract is a risk factor for vaginal GBS. Sexual activity and abnormal vaginal microflora are independent determinants of vaginal GBS colonization.
Le texte complet de cet article est disponible en PDF.Key words : group B Streptococcus, infection, sexual behavior, vaginal microflora
Plan
| This research was supported by contract N01-AI-75326 from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health and by Grant M01-RR000056 from the National Center for Research Resources of the National Institutes of Health and the General Clinical Research Centers. |
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| Reprints not available from the authors. |
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| Cite this article as: Meyn LA, Krohn MA, Hillier SL. Rectal colonization by group B Streptococcus as a predictor of vaginal colonization. Am J Obstet Gynecol 2009;201:76.e1-7. |
Vol 201 - N° 1
P. 76.e1-76.e7 - juillet 2009 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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