Transient Ischemic Attack: Risk Stratification and Treatment - 21/08/11

Doi : 10.1016/j.annemergmed.2008.05.019

Brett Cucchiara, MD ^a,^⁎ , Michael Ross, MD ^b
^a Department of Neurology, University of Pennsylvania, Philadelphia, PA
^b Department of Emergency Medicine, Emory University, Atlanta, GA.

Address for correspondence: Brett Cucchiara, MD, Department of Neurology, University of Pennsylvania Medical Center, 3 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104

Résumé

A major challenge facing the physician evaluating patients with transient ischemic attack is determining which patients are at highest short-term risk of stroke. A number of stratification schemes have been recently developed incorporating easily obtainable clinical information about the individual patient. Further, emerging data suggest a role for brain and vascular imaging in risk stratification. Many aspects of acute management of transient ischemic attack, such as which patients should be hospitalized and choice of acute antithrombotic therapy, remain controversial because of a lack of evidence from controlled trials. For longer-term prevention, there is much firmer evidence from multiple large randomized trials, and these data are reviewed in this article.

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Plan

Supervising editor: Allan B. Wolfson, MD

Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. BC has received honoraria for lectures from Boehringer Ingelheim and Bristol-Myers Squibb/Sanofi. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement.
This article was part of a supplement sponsored by Boehringer Ingleheim Pharmaceuticals, Inc.