Does labeling prenatal screening test results as negative or positive affect a woman’s responses? - 22/08/11
, Angela Fagerlin, PhD 1, 2, 3, Kristie Keeton, MD, MPH 4, Peter A. Ubel, MD 1, 2, 3, 5
Reprints: Brian J. Zikmund-Fisher, Center for Behavioral and Decision Sciences in Medicine, 300 North Ingalls Building, Rm 7C27, Ann Arbor, MI 48109-0429Résumé |
Objective |
We tested whether adding interpretive labels (eg, “negative test”) to prenatal genetic screening test results changes perceived risk and preferences for amniocentesis.
Study Design |
Women (N = 1688) completed a hypothetical pregnancy scenario on the Internet. We randomly assigned participants into 2 groups: high risk of fetal chromosomal problems (12.5/1000) or low risk (2/1000). After prenatal screening, estimated risk was identical (5/1000) for all participants, but results were provided either alone or with interpretive labels.
Results |
When receiving test results without labels, all participants react similarly. With labels, the participants who received “positive” or “abnormal” results reported a higher perceived risk (P < .001), greater worry (P < .001), and greater interest in amniocentesis (57% vs 37%; P < .001) than did the participants who received “negative” or “normal” results.
Conclusion |
Interpretive labels for test results can induce larger changes to a woman’s risk perception and behavioral intention than can numeric results alone, which create decision momentum. This finding has broad clinical implications for patient–provider communication.
Le texte complet de cet article est disponible en PDF.Key words : amniocentesis, decision-making, prenatal screening, risk
Plan
| Supported in part by the National Institutes for Health (R01 CA87595 and P50 CA101451), by a career development award from the American Cancer Society (MRSG-06-130-01-CPPB [B.J.Z-F.]), and by a Merit Review Entry Program early career award from the Department of Veterans Affairs (A.F.). |
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| The views expressed in this article are those of the authors and do not necessarily reflect the position or policy of the Department of Veterans Affairs. |
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| Cite this article as: Zikmund-Fisher BJ, Fagerlin A, Keeton K, Ubel PA. Does labeling prenatal screening test results as negative or positive affect women’s responses? Am J Obstet Gynecol 2007;197:528.e1-528.e6. |
Vol 197 - N° 5
P. 528.e1-528.e6 - novembre 2007 Retour au numéro
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