A new method to close the gastrotomy by using a cardiac septal occluder: long-term survival study in a porcine model - 22/08/11
Reprint requests: Jacques Marescaux, MD, IRCAD-EITS, University of Strasbourg, 1, place de l’hopital-Hopitaux Universitaires, 67091 Strasbourg, CEDEX-France.Strasbourg, France, Occlutech, Germany
Abstract |
Introduction |
Closure of the gastrotomy when performing transgastric procedures is one of the most challenging steps to overcome. Several methods of gastric closure have been described, but a simple and safe technique is still lacking.
Aim |
To evaluate the technical feasibility and safety of a new method of endoscopic gastric closure using a nitinol septal occluder in a porcine survival model.
Design |
Endoscopic animal experimental study in a porcine survival model.
Materials and Methods |
In 6 male pigs under general anesthesia, a 1-cm full-thickness gastrotomy was performed on the anterior body of the stomach and closed with a nitinol septal occluder (Occlutech). Postoperative follow-up included endoscopy and laparoscopy at 1, 2, 4, and 6 weeks after the initial procedure and endoscopy alone at weeks 8, 10, and 12.
Results |
All of the gastrotomy closures with the septal occluder were successful. At follow-up endoscopy and laparoscopy there were no signs of adhesions, peritonitis, or perigastric abscess formation at the gastrotomy site. At 12 weeks, 5 of 6 animals were thriving, with appropriate weight gain.
Conclusions |
Endoscopic gastrotomy closure with a septal occluder is technically feasible, safe, and effective in a survival porcine model.
Le texte complet de cet article est disponible en PDF.Abbreviations : MRI, NOTES, PET
Plan
Vol 66 - N° 4
P. 809-813 - octobre 2007 Retour au numéro
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