Endoscopic papillary balloon dilation for the management of bile duct stones in patients 85 years of age and older - 23/08/11
Reprint requests: Takeshi Tsujino, MD, Department of Gastroenterology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan.Tokyo, Japan
Abstract |
Background |
Endoscopic papillary balloon dilation (EPBD) is a possible alternative to endoscopic sphincterotomy for the treatment of bile duct stones. However, little information is available in the elderly.
Objective |
Our purpose was to evaluate the safety and efficacy of EPBD for bile duct stones in patients of 85 years of age and older.
Design |
Retrospective study from a single center.
Setting |
Tertiary care facility with experience in bile duct stone removal with EPBD.
Patients |
A total of 406 patients (74 patients ≥85 years old, group A; 332 patients <85 years old, group B) with bile duct stones underwent EPBD.
Main Outcome Measurements |
Efficacy and safety of EPBD between the 2 groups. Baseline patient characteristics were also evaluated.
Results |
The mean American Society of Anesthesiologists score in group A was significantly higher compared with that in group B (2.4 [0.5] vs 1.9 [0.7], P < .0001). Patients received anticoagulants more frequently and had larger and more numerous stones in group A than in group B with significant differences. Overall, bile duct clearance rates were similar in the 2 groups (91% vs 95%), but the mean number of sessions required for complete stone removal was significantly higher in group A (1.6 vs 1.4, P = .0081). The incidence of overall early complications after EPBD was lower in group A than in group B (2.7% vs 8.4%) but was not statistically different. None of the patients in group A had post-EPBD pancreatitis, whereas pancreatitis occurred in 5.7% in group B (P = .036). Bleeding was not observed after EPBD in 406 patients, including 7 patients in group A who received anticoagulation therapy at the time of EPBD. There was no significant difference in the cumulative stone nonrecurrence rate between group A and group B (log-rank test, P = .6225).
Conclusions |
EPBD is a safe and effective technique for the treatment of bile duct stones even in high-risk elderly patients without an increased risk of pancreatitis and bleeding. Because the evaluation of outcomes might be biased by our study design (an open study), further studies are needed.
Le texte complet de cet article est disponible en PDF.Abbreviations : ASA, EML, EPBD, EST
Plan
Vol 68 - N° 3
P. 477-482 - septembre 2008 Retour au numéro
Article précédent
- EUS accurately predicts the need for therapeutic ERCP in patients with a low probability of biliary obstruction
- Jan Janssen, Ali Halboos, Lucas Greiner
- Endoscopic balloon dilation of the sphincter of Oddi for stone extraction in the elderly: is the juice worth the squeeze?
- James A. DiSario
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