Risk of severe allergic reactions from the use of potassium iodide for radiation emergencies - 24/08/11
Reprint requests: Scott H. Sicherer, MD, Division of Allergy/Immunology, Jaffe Food Allergy Institute, Mount Sinai Hospital, Box 1198, One Gustave L. Levy Place, New York, NY 10029-6574.on behalf of the Adverse Reactions to Foods Committee and the Adverse Reactions to Drugs and Biologicals Committee New York, NY
Abstract |
Potassium iodide (KI) may be prescribed for widespread use in the event of a radiation emergency to prevent the uptake of radioactive iodide by the thyroid gland. The available literature was reviewed and expert opinion sought among members of the Adverse Reactions to Foods and the Adverse Reactions to Drugs and Biologicals Committees of the Academy to assemble evidenced-based conclusions regarding the risks of an allergic reaction to this therapy. This article describes the information leading to the following conclusions: (1) anaphylactoid reactions to radiocontrast media should not be considered evidence of KI allergy, (2) allergic contact dermatitis from iodine-containing antibacterial preparations should not be considered evidence of IgE antibody–mediated KI allergy or sensitivity, (3) IgE antibody–mediated allergy to seafood should not be considered evidence of KI allergy or sensitivity, and (4) physicians should ensure that persons are not allergic to inactive ingredients or components of the KI formulation prescribed.
Le texte complet de cet article est disponible en PDF.Key words : Potassium iodide allergy, radiocontrast, shellfish allergy
Abbreviations used : FDA, KI, RCM
Plan
| This Practice Paper is not to be construed as dictating an exclusive course of action, nor is it intended to replace the medical judgment of healthcare professionals. The unique circumstances of individual patients and environments are to be taken into account in any diagnosis and treatment plan. This statement reflects clinical and scientific advances as of the date of publication and is subject to change. |
Vol 114 - N° 6
P. 1395-1397 - décembre 2004 Retour au numéro
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