Monochromatic excimer light (308 nm) in patch-stage IA mycosis fungoides - 24/08/11
Abstract |
Recently, numerous studies have been reported concerning the treatment of early-stage mycosis fungoides (MF) with narrowband (311-nm) UVB, claiming a beneficial response. We have used for the first time a 308-nm monochromatic excimer light, a new kind of xenon-chloride lamp, in the treatment of patch stage IA MF. We treated 7 patch lesions in 4 patients with unequivocal clinicopathologic diagnosis of MF. All lesions achieved clinical and histologic complete remission. The number of weekly sessions varied from 4 to 11 (mean 6.5; median 5.5). The total UVB 308-nm irradiation dose ranged from 5 to 9.3 J/cm2 (mean 7.1 J/cm2; median 7 J/cm2). All lesions remained in stable complete remission after a follow-up of 3 to 28 months. No remarkable side effects were reported. Our preliminary results suggest that monochromatic excimer light phototherapy is a possibly very useful treatment modality in patch stage IA MF.
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Supported by the Ente Cassa di Risparmio di Firenze. Conflicts of interest: None identified. |
Vol 50 - N° 6
P. 943 - juin 2004 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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