Right ventricular strain rate and strain analysis in patients with repaired tetralogy of Fallot: possible interventricular septal compensation - 24/08/11
Abstract |
Background |
Indices such as strain rate (SR) and strain (ϵ) are free of geometric assumptions and, thus, may provide new insights into right ventricular (RV) function and compensatory mechanisms in repaired tetralogy of Fallot (TOF).
Methods |
All those with postoperative (>1 year) TOF had echocardiography evaluation of SR and ϵ indices along the RV lateral free wall (RVFW) and the interventricular septum (IVS) in the apical 4-chamber view. Pulmonary regurgitation, pulmonary stenosis, QRS duration, RV ejection fraction, and RV dimension were also measured and compared with control subjects.
Results |
There were 15 patients with TOF (7 ± 4 years old) 6 ± 3 years remote from surgical repair and 25 control subjects (10 ± 5 years old). In the patients with TOF, systolic and diastolic SR and ϵ in the RVFW were significantly reduced but were normal in the IVS. In the RVFW, reduced systolic SR and ϵ correlated with reduced RV ejection fraction (r = −0.7 [P < .01] and −0.6 [P < .03], respectively), and poorer early diastolic SR correlated with poorer RV ejection fraction (r = 0.7, P < .01).
Conclusions |
In patients with postoperative TOF, systolic and diastolic RV SR and ϵ were impaired in the RVFW but preserved in the IVS. We speculate that IVS myocardial function is preserved as a compensatory mechanism for impaired RVFW function.
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 | Supported by grants from American Heart Association Student Scholars in Cardiovascular Disease and Stroke; National Institutes of Health Medical Student Summer Research Fellowship, University of Cincinnati College of Medicine. |
Vol 17 - N° 4
P. 338-344 - avril 2004 Retour au numéro
Article précédent
- Myocardial acceleration during isovolumic contraction as a new index of right ventricular contractile function and its relation to pulmonary regurgitation in patients after repair of tetralogy of Fallot
- Manatomo Toyono, Kenji Harada, Masamichi Tamura, Fumio Yamamoto, Goro Takada
- Index of myocardial performance after early phase of myocardial infarction in relation to its location
- Federico Cacciapuoti, Alessandro Arciello, Michele Fiandra, Eleonora Manfredi, Fulvio Cacciapuoti, Diana Lama
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