Intraobserver and interobserver variability for the histologic diagnosis of chorioamnionitis - 25/08/11
, Heather Jeffery, MPH, PhD, MRCP (UK) a, c, Geoffrey Watson, FRCPA b, Peter Russell, MD, FRCPA b
Reprint requests: Martin Simmonds, Neonatal Fellow, R.P.A. Newborn Care, Level 3, East Wing, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050 Australia.Abstract |
Objectives |
The interobserver and intraobserver variability for the histopathologic diagnosis of chorioamnionitis was examined.
Study design |
Two examiners independently reviewed archived slides from 250 placentas. They were blinded to the original diagnosis and details of the pregnancy. Definitions for two important diagnoses were made and a protocol for recording information trialed before the study. Slides were examined under conditions reflecting normal working practice.
Results |
A high level of agreement for the diagnosis of chorioamnionitis and umbilical vessel vasculitis (κ range 0.78-0.81) between the examiners was found. Comparison of the agreement between each examiner and their original diagnosis was also excellent (κ range 0.90-0.91).
Conclusion |
This study has audited the reliability of the diagnosis of chorioamnionitis, a common and important placental finding. The reproducible and reliable degree of agreement demonstrated permits further research to be undertaken relating this diagnosis to adverse postnatal outcomes.
Le texte complet de cet article est disponible en PDF.Keywords : Chorioamnionitis, Interobserver variability
Plan
Vol 190 - N° 1
P. 152-155 - janvier 2004 Retour au numéro
Article précédent
- A fetal response to chorioamnionitis is associated with early survival after preterm birth
- Monica M Lahra, Heather E Jeffery
- Neuromorbidity in preterm twins in relation to chorionicity and discordant birth weight
- Adedayo L Adegbite, Shirley Castille, Stuart Ward, Rekha Bajoria
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