Xenograft transplantation - 25/08/11
Doi : 10.1016/j.atc.2004.05.005
Zain Khalpey, MRCS (Eng) a, b, c, Cody A. Koch, MPA a, b, c, d, Jeffrey L. Platt, MD ⁎, a, b, c, d 
a Transplantation Biology, Mayo Clinic, 200 First Street, SW, Medical Sciences Building 2-66, Rochester, MN 55905, USA
b Department of Surgery, Mayo Clinic, 200 First Street, SW, Medical Sciences Building 2-66, Rochester, MN 55905, USA
c Department of Immunology, Mayo Clinic, 200 First Street, SW, Medical Sciences Building 2-66, Rochester, MN 55905, USA
d Department of Pediatrics, Mayo Clinic, 200 First Street, SW, Medical Sciences Building 2-66, Rochester, MN 55905, USA
*Corresponding author. Mayo Clinic, 200 First Street, SW, Medical Sciences Building 2-66, Rochester, MN 55905
Résumé |
Interest in xenotransplantation has increased because conventional organ transplantation has been limited by a shortage of human organs. Although xenotransplantation could alleviate the existing and anticipated need for tissues and organs, the application is hindered by various biologic obstacles. This article reviews the basis for the demand for xenotransplantation, the obstacles to clinical application, and potential approaches to overcoming those obstacles.
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© 2004
Elsevier Inc. Tous droits réservés.
Vol 22 - N° 4
P. 871-885 - décembre 2004 Retour au numéro
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- Jeffrey D. Punch
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- Marie Csete
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