Effect of exercise training on endothelial function in men with coronary artery disease - 26/08/11
Doi : 10.1016/j.amjcard.2003.11.032
David G. Edwards, PhD a, ⁎ 
, Richard S. Schofield, MD b, Shannon L. Lennon, PhD d, Gary L. Pierce, MS c, Wilmer W. Nichols, PhD b, Randy W. Braith, PhD c
, Richard S. Schofield, MD b, Shannon L. Lennon, PhD d, Gary L. Pierce, MS c, Wilmer W. Nichols, PhD b, Randy W. Braith, PhD c a Department of Kinesiology, University of New Hampshire, Durham, New Hampshire, USA
b Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA
c Center for Exercise Science, University of Florida, Gainesville, Florida, USA
d Myocardial Biology Unit, Boston University Medical Center, Boston, Massachusetts, USA
*Dr. Edwards' address is: Department of Kinesiology, New Hampshire Hall, 124 Main Street, Durham, New Hampshire 03824, USA
Abstract |
The objective of this study was to investigate the effects of 12 weeks of standard cardiac rehabilitation on endothelial function, oxidative stress, and antioxidant defenses in patients with coronary artery disease. Twelve weeks of endurance exercise training led to an improvement in endothelial function as measured by brachial artery flow-mediated dilation (7.9% at baseline vs 11.1% at 12 weeks). Exercise training resulted in increased plasma nitrite and nitrate levels, increased plasma superoxide dismutase activity, and decreased oxidative stress.
Le texte complet de cet article est disponible en PDF. | This work was supported by a predoctoral fellowship from the American Heart Association Florida Affiliate No. 0010079B, St. Petersburg, Florida, and the Michael Pollock Memorial Grant from Life Fitness Academy, Franklin Park, Illinois (both to DGE). |
© 2004
Excerpta Medica Inc. Tous droits réservés.
Vol 93 - N° 5
P. 617-620 - mars 2004 Retour au numéro
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