Special considerations in the evaluation and management of uveitis in children - 26/08/11

Doi : 10.1016/S0002-9394(03)00314-3

Gary N Holland, MD ^a,^b,^⁎ , E.Richard Stiehm, MD ^c
^a Ocular Inflammatory Disease Center, Jules Stein Eye Institute (G.N.H.), Los Angeles, California, USA
^b Department of Ophthalmology (G.N.H.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
^c Department of Pediatrics (E.R.S.), David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California, USA

^*Inquiries to Gary N. Holland, MD, Jules Stein Eye Institute, 100 Stein Plaza, UCLA, Los Angeles, CA 90095-7003, USA; fax: (310) 794-7906;

Abstract

Purpose

To review issues related to the diagnosis, examination, and treatment of children with uveitis that are important for ophthalmologists.

Design

Literature review.

Methods

A review was made of pertinent reports from the medical literature, with commentary based on the authors’ experiences and on discussions at an international workshop.

Results

There are differences between children and adults in the differential diagnosis and manifestations of uveitis that should be considered during evaluation. There may be a higher risk of some ocular complications such as uveitic glaucoma, and the presence of other unique complications, such as amblyopia, in young patients during follow-up. With regard to treatment, children with uveitis may have unique dosing requirements and drug-associated risks such as growth retardation with systemic corticosteroids that must be considered. Examination and treatment may also be more difficult with children because of problems with patient cooperation.

Conclusions

There are unique patient care issues associated with uveitis in children that must be considered by care providers. Attention to these issues will improve the well-being of this patient population.

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Plan

Patient populations

Differential diagnosis

Complications of disease

Nonsteroidal anti-inflammatory drugs

Drug side effects

An approach to medical treatment

Management of complications

Cataract extraction

Glaucoma management

Monitoring and compliance

Summary

InternetAdvance publication at ajo.com March 24, 2003.
Doctor Holland was supported in part by Research to Prevent Blindness, Inc, New York, New York, the Skirball Foundation, Los Angeles, California, and the David May II Endowed Professorship, and is a recipient of a Research to Prevent Blindness Physician-Scientist Award.

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Vol 135 - N° 6

P. 867-878 - juin 2003 Retour au numéro

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Special considerations in the evaluation and management of uveitis in children - 26/08/11

Abstract

Purpose

Design

Methods

Results

Conclusions

Plan

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