Endoscopic and oncologic outcomes after endoscopic resection for early gastric cancer: 1370 cases of absolute and extended indications - 27/08/11
Reprint requests: Hwoon-Yong Jung, MD, PhD, AGAF, Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute, No. 388-1 Pungnap-2 dong, Songpa-gu, Seoul, 138-736, KoreaRésumé |
Background |
Current guidelines for endoscopic management such as EMR and endoscopic submucosal dissection (ESD) in early gastric cancer (EGC) are in evolution, with broader indication criteria.
Objective |
To determine the clinical outcomes of endoscopic treatment, based on absolute indication and extended indication criteria and endoscopic methods.
Design |
Retrospective study.
Setting |
Tertiary-care, academic medical center.
Patients |
EMR or ESD was performed on 1627 cases of EGC in 1447 patients from July 1994 to January 2009.
Intervention |
EMR and ESD.
Main Outcome Measurements |
Clinical outcomes of EGC after EMR or ESD, based on the indication criteria.
Results |
Although the complete resection rate was higher (95.9% vs 88.4%; P < .001), and the complication rate was lower (6.8% vs 9.8%; P = .054) in the absolute than in the extended indication group, there was no between-group difference in the local recurrence rate (0.9% vs 1.1%; P = .783) at a median follow-up period of 32 months (interquartile range 22-48 months). In the extended indication group, ESD resulted in a significantly higher complete resection rate than EMR (83.0% vs 91.1%; P = .006).
Limitations |
Retrospective study.
Conclusion |
ESD in the extended indication group showed acceptable clinical outcomes with a relatively high complete resection rate and a low local recurrence rate.
Le texte complet de cet article est disponible en PDF.Abbreviations : EGC, ESD
Plan
| DISCLOSURE: All authors disclosed no financial relationships relevant to this publication. |
Vol 74 - N° 3
P. 485-493 - septembre 2011 Retour au numéro
Article précédent
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- Endoscopic resection for early gastric cancer: one piece is better than dash to pieces
- Philip Wai-yan Chiu, Joseph Jao-yiu Sung
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