Five-year comprehensive outcomes evaluation in 181 patients after laparoscopic Nissen fundoplication - 28/08/11
Abstract |
Background |
We conducted an objective followup of 181 patients after laparoscopic Nissen fundoplication during a 5-year period after surgery.
Study design |
Patients underwent 24-hour pH recording, esophageal manometry, and symptom score assessment for six gastroesophageal reflux disease symptoms preoperatively and at 6 months, 2 years, and 5 years after surgery.
Results |
Laparoscopic fundoplication was associated with a significant (p < 0.0001) increase in lower esophageal sphincter pressure and a significant (p < 0.0001) drop in duration of acid reflux in 24 hours, and symptom score, 6, 24, and 60 months after surgery when compared with preoperative values. Twenty-one patients (12%) have experienced recurrence of reflux-type symptoms, but only six have required repeat surgery. Lower esophageal sphincter tone dropped between 6 months and 5 years after surgery, but was still an effective antireflux barrier. Patient satisfaction with surgery dropped over the 5-year followup but remained high, at 86%, after 5 years.
Conclusions |
Laparoscopic Nissen fundoplication remains an effective antireflux procedure at 5 years.
Le texte complet de cet article est disponible en PDF.Abbreviations : GERD, gastroesophageal reflux disease, LES, lower esophageal sphincter, PPI, proton pump inhibitor
Plan
 | No competing interests declared. |
Vol 196 - N° 1
P. 51-57 - janvier 2003 Retour au numéro
Article précédent
- Prognosis and management of extramammary paget’s disease and the association with secondary malignancies
- Jean-Pierre E.N Pierie, Umar Choudry, Alona Muzikansky, Dianne M Finkelstein, Mark J Ott
- Invited commentary
- Carlos Pellegrini
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?