Postresuscitation myocardial dysfunction has become increasingly recognized as a major contributor to the poor long-term outcome results with current resuscitation efforts. Both systolic and left ventricular abnormalities are readily identified following successful resuscitation. The global myocardial stunning seen during this period can be severe and, unless supported, can lead to death. Although the exact mechanism of postresuscitation global myocardial dysfunction is not yet known, a number of factors that contribute have been identified, as well as several potential treatment strategies.