Chest computerized tomography in the evaluation of uveitis in elderly women - 02/09/11

Doi : 10.1016/S0002-9394(02)01333-8

Peter K Kaiser, MD ^a,^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.}}, Careen Y Lowder, MD, PhD ⁎, ^a,^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.}} , Preston Sullivan, MD ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^a, Steven R Sanislo, MD ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^a, Gregory S Kosmorsky ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^a : DO, Moulay A Meziane, MD ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^b, Thomas W Rice, MD ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^c, Scott D Smith, MD, MPH ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^a, David M Meisler, MD ^{^{1
Each author states that he/she has no proprietary interest in the development or marketing of this or any competing piece of equipment.},}^a
^a Division of Ophthalmology, Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA (P.K.K., C.Y.L., P.S., S.R.S., G.S.K., S.D.S., D.M.M.)
^b Division of Radiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA (M.A.M.)
^c Division of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA (T.W.R.)

^*Reprint requests to Careen Y. Lowder, MD, PhD, Division of Ophthalmology, Desk i-32, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA; fax (216) 445-2226

Abstract

PURPOSE: To describe the usefulness of chest computerized tomography (CT) in the evaluation of uveitis in elderly women and the clinical characteristics of patients with an abnormal chest CT scan.

DESIGN: Prospective noncomparative case series.

METHODS: We evaluated 30 elderly women, aged 61–83 years, with chronic iritis, vitritis, or choroiditis and with no definitive cause for their uveitis. All patients underwent a battery of diagnostic laboratory studies and chest CT.

RESULTS: The diagnostic examination in most patients included serum angiotensin converting enzyme level, serum lysozyme, rapid plasma reagin level, fluorescent treponemal antibody-absorption test, purified protein derivative skin test, and chest x-rays. Chest CT performed on all patients showed parenchymal, mediastinal, and/or hilar adenopathy in 17 patients (57%). Histopathologic confirmation of sarcoidosis with noncaseating granulomas in the biopsy specimens was obtained in 14 patients: eight by mediastinoscopy, two by bronchoscopy, two by conjunctival biopsy, one by nasal biopsy, and one by vitreous biopsy.

CONCLUSIONS: Chest CT can be useful in elderly female patients with chronic uveitis for identifying mediastinal lymphadenopathy and other lesions suggestive of sarcoidosis, as well as to help guide tissue confirmation and to rule out other diagnoses including lymphoma.

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Vol 133 - N° 4

P. 499-505 - avril 2002 Retour au numéro

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Chest computerized tomography in the evaluation of uveitis in elderly women - 02/09/11

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