Interstitial granulomatous dermatitis with cutaneous cords and arthritis: A disorder associated with autoantibodies - 02/09/11
Abstract |
Interstitial granulomatous dermatitis with arthritis is a new entity characterized by linear or arciform subcutaneous cords. We describe a patient presenting with typical cutaneous lesions extending from the anterior and posterior part of the axillae to the flank. The lesions had been present for 6 years with flares and remission. Histopathologic examination revealed a bandlike infiltrate of histiocytes in the reticular dermis with focal areas of palisading around necrotic collagen bundles. A few atypical histiocytes were also present. As previously described, it was associated with serologic findings of an autoimmune disease, especially high titers of anti-DNA antibodies. The possible inclusion of the interstitial granulomatous dermatitis in the continuous spectrum of the palisaded neutrophilic and granulomatous dermatitis of immune complex disease is also discussed. (J Am Acad Dermatol 2001;45:286-91.)
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Reprint requests: Professeur Dominique Leroy, Service de Dermatologie, Centre Hospitalier Universitaire, Avenue Georges Clemenceau, 14033 Caen Cedex, France. |
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J Am Acad Dermatol 2001;45:286-91 |
Vol 45 - N° 2
P. 286-291 - août 2001 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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