EXERCISE AND THROMBOSIS - 03/09/11
Résumé |
Physical inactivity represents a major cardiovascular risk factor of particular importance in Western industrialized countries, where automation and other technologies have contributed to a continuous decrease in physical activity at work and at home. Although there are various forms of physical exercise, in the context of cardiovascular health the authors are almost exclusively concerned with long-term endurance exercise. Meta-analysis of prospective studies has shown an at least twofold increase in coronary risk in sedentary compared to active, initially healthy subjects, as well as in patients with manifest coronary heart disease (CHD).3 Conversely, physical activity during leisure time, mainly aerobic endurance exercise, is an effective way to reduce cardiovascular morbidity and mortality, and total mortality; to reduce symptoms in patients with angina, and to improve exercise tolerance, functional capacity, psychological well-being, and quality of life.43 The true impact of regular physical activity on these end points most probably is underestimated. From a public health perspective, engagement in physical exertion represents a cost-effective way to improve cardiovascular health in the general population.
The health benefit conferred by regular aerobic exercise may be mediated in several ways. It has been found to be associated with lower smoking rates, lower body weight, lower cholesterol levels, higher high-density lipoprotein (HDL) cholesterol levels, lower pulse and blood pressure, and other positive physiologic effects, including an improvement in the balance of the hemostatic system by reducing thrombogenic factors and increasing the fibrinolytic capacity.8, 35
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| Address reprint requests to Wolfgang Koenig, MD, Department of Internal Medicine II–Cardiology, University of Ulm, Medical Centre, Robert-Koch-Str. 8, D-89081 Ulm, Germany, e-mail: wolfgang.koenig@medizin.uni-ulm.de |
Vol 19 - N° 3
P. 389-400 - août 2001 Retour au numéro
Article précédent
- EXERCISE AND AUTONOMIC FUNCTION IN HEALTH AND CARDIOVASCULAR DISEASE
- Eric T. Rosenwinkel, Daniel M. Bloomfield, M. Allison Arwady, Rochelle L. Goldsmith
- EXERCISE ELECTROCARDIOGRAM TESTING AND PROGNOSIS : Novel Markers and Predictive Instruments
- Michael S. Lauer
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