CANCER AND AGING : An Evolving Panorama - 04/09/11
Résumé |
Today, the treatment of neoplastic diseases reflects a changing demographic situation with an aging population. The framework of information on which these treatments are based is in continuous development because of new insights into the biology of cancer and new diagnostic and therapeutic developments.
This article explores the influence of age on the incidence, biology, clinical presentation, prognosis, and treatment of cancer. It highlights the areas in which cancer and age interact and in which rapidly accruing information may determine clinical intervention and stimulate further research.
Currently, cancer is the second most common cause of death among persons aged 65 years and over. Unlike the mortality of cardiovascular diseases, which is declining among persons of all ages, the mortality of cancer is rising for older individuals (Figure 1). 12 Approximately 50% of all neoplasms occur in the 12% of the population aged 65 years and older, and this percentage will increase with the expansion of the older population.66
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| Address reprint requests to Lodovico Balducci, MD, H. Lee Moffitt Cancer Center, University of South Florida College of Medicine, 12902 Magnolia Drive, Tampa, FL 33612–9497 |
Vol 14 - N° 1
P. 1-16 - février 2000 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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