Evidence for elevated telomerase activity in small cell carcinoma of the bladder - 05/09/11
Doi : 10.1016/S0090-4295(00)00635-X
C Selli a, ⁎, S Gelmini b, C.A Scott c, A Crisci a, G Giannarini a, C Orlando b
a Department of Urology, University of Udine, Udine, Italy
b Department of Pathology, University of Udine, Udine, Italy
c Department of Clinical Physiopathology, University of Florence, Florence, Italy
*Address for correspondence: Cesare Selli, M.D., Clinica Urologica, Policlinico Universitario, I-33013 Gemona del Friuli, Udine, Italy
Abstract |
Telomerase activity was found to be elevated using a quantitative assay on snap-frozen protein extracts of exfoliated cells in urine and bladder washings and tumor tissue obtained from a male patient with small cell carcinoma of the bladder. To the best of our knowledge, this is the first demonstration of elevated values of telomerase activity in genitourinary small cell carcinoma and is in keeping with the findings in primary lung locations.
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© 2000
Elsevier Science Inc. Tous droits réservés.
Vol 56 - N° 2
P. 331 - août 2000 Retour au numéro
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