Brainstem encephalitis resulting from Epstein-Barr virus mimicking an infiltrating tumor in a child - 06/09/11
, ⁎, Marianna Bugiani, MD , Federica Zibordi, MD , Paola Cinque, MD ‡, Alberto Bizzi, MD † Department of Neuropediatrics, Istituto Nazionale Neurologico Milan Italy Abstract |
A case of a child with subacute neurologic features and imaging findings consistent with a brainstem encephalitis that was discovered to be related to a primary central nervous system infection caused by Epstein-Barr virus is presented. A brainstem tumor was initially suspected, but a correct diagnosis was formulated on the basis of the favorable clinical course and the detection of positive Epstein-Barr virus serology. In contrast to a prompt recovery of neurologic signs the neuroimaging alterations persisted for a longer time. The present report emphasizes the possible role of Epstein-Barr virus in the pathogenesis of infectious neurologic disorders in childhood, underlining the unusual presentation of a brainstem encephalitis, and considers the discrepancy between the course of neurologic features and the evolution of imaging alterations.
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Vol 22 - N° 2
P. 130-132 - février 2000 Retour au numéro
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