Scleromyxedema - 07/09/11
Abstract |
Scleromyxedema is a sclerotic variant of papular mucinosis, in which lichenoid papules and scleroderma-like features are present. We describe a patient with scleromyxedema with IgG type lambda chain paraprotein, a systemic sclerosis-like illness, and myositis. The patient’s serum contained Scl 70 antibodies, characteristic of scleroderma. Electromyography showed signs of acute myositis and the creatine phosphokinase (CPK) level was elevated. Multiply passaged fibroblasts from the patient’s skin lesions showed altered growth response in vitro. The patient was treated with cyclosporin (4 mg/kg/day) with improvement. (J Am Acad Dermatol 1999;40:343-6.)
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 | This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology. |
| From the Department of Dermatology,a Albert Szent-Gyorgyi Medical University, Szeged, Hungary, and Department of Dermatology,b University of Michigan. |
 | Reprint requests: Zsuzsanna Bata-Csorgo, MD, Department of Dermatology, Szent-Gyorgyi Medical School, Szeged, PO Box 480, 6701 Hungary. |
| 0190-9622/99/$8.00 + 0 16/4/92746 |
Vol 41 - N° 2S
P. 343-346 - août 1999 Retour au numéro
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