OSTEOCHONDRAL ALLOGRAFT TRANSPLANTATION - 08/09/11
Résumé |
Focal articular cartilage defects in the knee pose a difficult challenge. Advances in the understanding of biologic principles and application of newer clinical techniques in repair, regeneration, and transplantation of articular cartilage have generated enormous interest in both the orthopedic community and the general public. Nonetheless, treatment of cartilage lesions is still considered an unsolved clinical and scientific problem. Fresh osteochondral allografting for localized defects in articular cartilage of the knee is one approach that has perhaps the longest clinical experience.1, 3, 4 At least three centers in North America are routinely performing fresh allografting procedures, with experience extending over two decades. Although there are differences in patient selection and technique among these groups, basic principles and reported clinical outcomes are quite similar.1, 3, 4, 6, 10
In 1983, a program was developed at the University of California, San Diego, to investigate the clinical outcome of transplantation of fresh osteochondral shell allografts in the knee. Approximately 200 procedures have been performed to date. The overall experience has been extremely positive and has encouraged the authors to continue to use this technique in the treatment of focal chondral and osteochondral defects and to investigate its application in more extensive cartilage disease states.
Le texte complet de cet article est disponible en PDF.Plan
| Address reprint requests to William D. Bugbee, MD, Department of Orthopaedics, University of California, San Diego, 200 West Arbor Drive, San Diego, CA 92103-8894 |
Vol 18 - N° 1
P. 67-75 - janvier 1999 Retour au numéro
Article précédent
- OSTEOCHONDRAL MOSAICPLASTY FOR THE TREATMENT OF FOCAL CHONDRAL AND OSTEOCHONDRAL LESIONS OF THE KNEE AND TALUS IN THE ATHLETE : Rationale, Indications, Techniques, and Results
- Gary Kish, László Módis, László Hangody
- OPTIONS IN MENISCAL REPAIR
- Damian M. Rispoli, Mark D. Miller
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?