DEVELOPING SURGICAL INTERVENTION CRITERIA FOR THORACIC AORTIC ANEURYSMS - 08/09/11
Résumé |
Thoracic aortic aneurysms (TAA) are critical conditions frequently requiring operative intervention in order to prevent rupture, dissection, and death.25 The decision to operate on the thoracic aorta is relatively straightforward for patients without significant operative contraindications who present with very large, rapidly expanding, or symptomatic ascending or descending TAA. Determining whether surgery is indicated, however, is far more complex for asymptomatic patients with a gradually expanding, moderately sized thoracic aorta. In deciding when to operate, the surgeon must weigh the benefits of resection against the operative risks. The ultimate objective is to select patients for whom the operative risks are justified. Current recommendations for surgical intervention have been largely based on clinical judgment, with a paucity of hard scientific and statistical data regarding the appropriate size criterion for surgical intervention.
Variation in the present management of patients with TAA reflects existing limitations in the state of medical knowledge. Adding to this uncertainty are the inconsistencies in the results of published studies, which have endeavored to estimate growth rates of TAA and to identify risk factors for complications. In addition, there is often difficulty in evaluating the validity of the statistical evidence presented in a given study. The present report expands on an earlier study examining these issues,4 and includes larger patient cohorts and longer follow-up.
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| Address reprint requests to John A. Elefteriades, MD, Section of Cardiothoracic Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510 |
Vol 17 - N° 4
P. 827-839 - novembre 1999 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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