Elevated adrenomedullin in the vitreous of patients with proliferative vitreoretinopathy - 08/09/11
Abstract |
PURPOSE: To explore the possible involvement of adrenomedullin in the pathophysiology of proliferative vitreoretinopathy.
METHODS: The radioimmunoassay technique was used to determine immunoreactive adrenomedullin concentrations in the vitreous fluid from 41 eyes of 41 patients undergoing vitrectomy for a variety of retinal conditions, including proliferative vitreoretinopathy, proliferative diabetic retinopathy, age-related macular degeneration, and macular hole.
RESULTS: Immunoreactive adrenomedullin levels in the vitreous of patients with proliferative vitreoretinopathy were significantly higher than those of patients with proliferative diabetic retinopathy (P < .005), age-related macular degeneration (P < .001), and macular hole (P < .0001).
CONCLUSION: Adrenomedullin may be involved in the pathophysiology of proliferative vitreoretinopathy.
Le texte complet de cet article est disponible en PDF.Vol 128 - N° 6
P. 765-767 - décembre 1999 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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