Repeat liver resection for recurrent colorectal liver metastases - 08/09/11
Abstract |
Background: This study aimed to delineate the role of surgery for recurrent colorectal cancer in the liver and to identify prognosticators for better patient selection and outcome.
Methods: Data from 90 repeat hepatectomies (second = 75; third = 12; fourth = 3) for recurrent colorectal cancer were collected.
Results: After the second hepatectomy, the 3- and 5-year survival rates were 48% and 31%, respectively. Twenty-seven percent (20 of 75) of patients are alive without recurrence after a median follow-up of 27 months, and 9 survived more than 5 years. Four or more tumors, positive regional lymph node metastases, concomitant extrahepatic disease, and residual tumor were independent poor prognostic factors after the second hepatectomy.
Conclusions: Repeat hepatectomy should be applied for recurrent colorectal cancer, when curative removal of the tumor is possible, although the benefit from treatment was limited in a patient with regional lymph node metastases, 4 or more metastases, or extrahepatic disease.
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 | This study was supported in part by a grant-in-aid for Cancer Research from the Ministry of Health and Welfare of Japan. |
Vol 178 - N° 4
P. 275-281 - octobre 1999 Retour au numéro
Article précédent
- An aggressive resectional approach to cystic neoplasms of the pancreas
- Karen D Horvath, John A Chabot
- Utility of 18F-FDG positron emission tomography scanning on selection of patients for resection of hepatic colorectal metastases
- Yuman Fong, Pierre F Saldinger, Timothy Akhurst, Homer Macapinlac, Henry Yeung, Ronald D Finn, Alfred Cohen, Nancy Kemeny, Leslie H Blumgart, Steven M Larson
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