Triple viral retinitis diagnosed by polymerase chain reaction of the vitreous biopsy in a patient with richter syndrome - 09/09/11
Abstract |
PURPOSE: To report the evaluation and identification of herpes viruses associated with retinitis in a patient with Richter syndrome.
METHODS: Diagnostic vitrectomy was performed on a patient with systemic leukemia and retinitis. The vitreous sample was evaluated by cytology, analysis of cytokines by ELISA, and detection of virus by polymerase chain reaction.
RESULTS: The vitreous biopsy specimen showed no malignant cells but predominant CD8+ lymphocyte infiltration with elevated interferon gamma and interleukin-6. DNA amplification and Southern blot analysis demonstrated DNA of herpes simplex, varicella-zoster, and cytomegalovirus.
CONCLUSION: Retinitis associated with multiple viruses in the vitreous biopsy may mimic leukemic infiltration in the eye.
Le texte complet de cet article est disponible en PDF.Vol 126 - N° 5
P. 732-733 - novembre 1998 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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