BIOCHEMICAL TESTING OF THYROID FUNCTION - 10/09/11
Résumé |
Over the past decade it has been generally accepted that the serum thyrotropin (TSH) represents the best biochemical marker of thyroid function when measured using an adequately sensitive assay. Considerable debate centers on the role of other thyroid function tests in supplementing TSH and on the recommendations as to which patients should be tested. In the current cost-conscious era, significant issues focus on cost-effectiveness and medical outcomes. Routine laboratory testing, which has been a mainstay of medicine in the United States for many years, is now being closely scrutinized by both health insurance companies and managed care organizations. Algorithms and guidelines for thyroid function testing have been published by Klee and Hay 20, 21 and others, 3, 5, 8, 13, 23 including various medical societies. 2, 10, 19, 25, 28, 30, 31 These guidelines generally are based on pathophysiologic principles and practice consensus; few have been derived from actual practice outcomes data. Recently, some outcomes studies have been conducted, the results of which support some parts of the guidelines and question others. These issues are reviewed in this article.
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| Address reprint requests to George G. Klee, MD, PhD, FCAP Mayo Clinic 360 Hilton Building 200 SW First Street Rochester, MN 55905 This work was supported in part by Cooperative Agreement No. U50/CCU512260-01 from the Centers for Disease Control and Prevention. |
Vol 26 - N° 4
P. 763-775 - décembre 1997 Retour au numéro
Article précédent
- CLINICAL AND BIOCHEMICAL EVALUATION OF CUSHING'S SYNDROME
- Christoph A. Meier, Beverly M.K. Biller
- CHANGING CONCEPTS IN THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES
- Hossein Gharib
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